Author

A. Espinosa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Cancer Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

W. A. Nyberg· 2 shared A. Ascani· 1 shared A. Benrick· 1 shared A. M. Figueroa· 1 shared A. Zhao· 1 shared C. Svensson· 1 shared D. A. Velasquez Pulgarin· 1 shared D. A. Velasquez-Pulgarin· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBioengineering

W. A. Nyberg

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Author profile →

6 papers

Recent·Most cited

Androgens modulate the immune profile in a mouse model of polycystic ovary syndrome

S. Torstensson, A. Ascani, S. Risal, H. Lu, A. Zhao, A. Espinosa, E. Lindgren, M. H. Johansson, G. Eriksson, M. Barakat, M. C. I. Karlsson, C. Svensson, A. Benrick, E. Stener-Victorin

This study shows that androgen exposure in a mouse PCOS model alters immune cell populations in reproductive and metabolic tissues, with effects mediated through androgen receptors.

bioRxiv · Feb 22, 2024Immunology

Dnmt3a mutations limit normal and autoreactive Tfh differentiation

Y. Shen, Z. Li, S. V. Boddul, Z. Kasza, A. Espinosa, L. Klareskog, F. Wermeling

This study shows that Dnmt3a mutations impair Tfh differentiation, contributing to autoimmune joint inflammation and reduced immune responses.

bioRxiv · Feb 16, 2024 · PreprintImmunology

Pseudomonas aeruginosa shows between and within strains heterogeneity in virulence phenotype after passive exposure to zebrafish (Danio rerio) and nematodes (Caenorhabditis elegans)

D. Azulai, A. Espinosa, M. Talamantes, H. L. Bennett, G. G. Perron

This study shows that Pseudomonas aeruginosa strains exhibit virulence differences when passively exposed to zebrafish and nematodes.

bioRxiv · Nov 27, 2023 · PreprintMicrobiology

Light induced expression of gRNA allows for optogenetic gene editing of T lymphocytes in vivo

D. A. Velasquez Pulgarin, N. Pelo, L. Ferrandiz, T. Trselic, W. A. Nyberg, G. L. Bowlin, A. Espinosa

This paper introduces BLU-VIPR, an optogenetic CRISPR tool that enables precise spatiotemporal gene editing in T lymphocytes in vivo by regulating gRNA production with blue light.

bioRxiv · Nov 9, 2023Bioengineering

Effects of Aerobic Exercise in Hepatic Lipid Droplet-Mitochondria interaction in Non-alcoholic Fatty Liver Disease

J. C. Borquez, F. Diaz-Castro, F. Pino-de la Fuente, K. Espinoza, A. M. Figueroa, I. Martinez-Ruiz, V. Hernandez, I. Lopez-Soldado, R. Ventura, A. Espinosa, V. Cortes, M. I. Hernandez-Alvarez, R. Troncoso

This study shows aerobic exercise reduces hepatic lipid droplet-mitochondria interaction in NAFLD models, correlating with lower disease severity.

bioRxiv · Jan 31, 2023 · PreprintPhysiology

Melanoma plasticity is controlled by a TRIM28-JUNB mediated switch

W. A. Nyberg, T. He, M. Sjostrand, D. A. Velasquez-Pulgarin, L. Pelle, R. Covacu, A. Espinosa

This paper identifies TRIM28-JUNB as a regulatory switch controlling melanoma phenotype switching between invasive and proliferative states.

bioRxiv · Sep 20, 2019 · PreprintCancer Biology