WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration
A. Coulter, V. Cortes, C. Theodore, R. Cianciolo, R. Korstanje, K. Campellone
This study shows WHAMM is essential for kidney reabsorption and autophagosome membrane closure by polymerizing actin, with loss of WHAMM causing albuminuria and autophagy defects.
bioRxiv · Jan 22, 2024Cell Biology