The P387 Thrombospondin-4 Variant Promotes Accumulation of Macrophages in Atherosclerotic Lesions
S. Muppala, M. T. Rahman, I. Krukovets, D. Verbovetskiy, E. Pluskota, A. Fleischman, D. G. Vince, E. F. Plow, O. Stenina-Adognravi
This study investigates the role of the P387 TSP4 variant in promoting macrophage accumulation in atherosclerotic lesions, finding it enhances macrophage adhesion and inflammation in both mice and humans.
bioRxiv · Jun 11, 2019Pathology