Liver X Receptor regulates Th17 and RORγt+ Treg cells by distinct mechanisms
S. M. Parigi, S. Das, A. Frede, R. F. Cardoso, K. P. Tripathi, C. Donas, Y. O. O. Hu, L. Engstrand, J.-A. Gustafsson, E. J. Villablanca
This study shows that Liver X Receptor (LXR) regulates RORγt+ Treg and Th17 cells in the mesenteric lymph node through distinct mechanisms, with microbiota transfer partially affecting Th17 expansion.
bioRxiv · Oct 25, 2019Immunology