Author

J.-A. Gustafsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Nadal· 2 shared J. A. Encinar· 2 shared J. Martinez-Pinna· 2 shared L. Marroqui· 2 shared R. M. Medina-Gali· 2 shared R. S. Dos Santos· 2 shared A. A. Perez-Serna· 1 shared A. Frede· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersPhysiology

A. Nadal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

G protein-coupled estrogen receptor activation by Bisphenol-A disrupts protection from apoptosis conferred by estrogen receptors ERα and ERβ in pancreatic beta cells

I. Babiloni-Chust, R. S. Dos Santos, R. M. Medina-Gali, A. A. Perez-Serna, J. A. Encinar, J. Martinez-Pinna, J.-A. Gustafsson, L. Marroqui, A. Nadal

This paper shows that BPA induces apoptosis in pancreatic beta cells by reducing ERβ heterodimers, while GPER activation by G1 has a similar effect, highlighting a novel mechanism of endocrine disruption.

bioRxiv · Jan 31, 2022Physiology

Bisphenol-S and Bisphenol-F alter mouse pancreatic β-cell ion channel expression and activity and insulin release through an estrogen receptor ERβ mediated pathway

L. Marroqui, J. Martinez-Pinna, M. Castellano-Munoz, R. S. Dos Santos, R. M. Medina-Gali, S. Soriano, I. Quesada, J.-A. Gustafsson, J. A. Encinar, A. Nadal

This study shows BPS and BPF affect mouse β-cell ion channels and insulin release via ERβ pathways, with effects absent in ERβ knockout mice.

bioRxiv · Sep 30, 2020Pharmacology & Toxicology

Estrogen receptor β exerts tumor suppressive effects in prostate cancer through repression of androgen receptor activity

A. M. Strom, S. Chaurasiya, S. M. Widmann, C. M. Botero, C.-Y. Lin, J.-A. Gustafsson

This study shows that estrogen receptor β suppresses prostate cancer by reducing androgen receptor activity through gene expression and metabolic changes.

bioRxiv · Nov 20, 2019Cancer Biology

Liver X Receptor regulates Th17 and RORγt+ Treg cells by distinct mechanisms

S. M. Parigi, S. Das, A. Frede, R. F. Cardoso, K. P. Tripathi, C. Donas, Y. O. O. Hu, L. Engstrand, J.-A. Gustafsson, E. J. Villablanca

This study shows that Liver X Receptor (LXR) regulates RORγt+ Treg and Th17 cells in the mesenteric lymph node through distinct mechanisms, with microbiota transfer partially affecting Th17 expansion.

bioRxiv · Oct 25, 2019Immunology