Author

A. Gondane

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Thomas· 1 shared D. Duveau· 1 shared H. M. Itkonen· 1 shared M. Loda· 1 shared S. Pallasaho· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

C. Thomas

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1 paper

Recent·Most cited

Compromised CDK12 activity causes dependency on the non-essential spliceosome components

S. Pallasaho, A. Gondane, D. Duveau, C. Thomas, M. Loda, H. M. Itkonen

This study shows that compromised CDK12 activity in prostate cancer cells leads to addiction to non-essential spliceosome components and lower DNA methylation, suggesting potential therapeutic targets.

bioRxiv · Dec 7, 2021 · PreprintCancer Biology