Author

S. Pallasaho

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

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A. Gondane· 1 shared C. Thomas· 1 shared D. Duveau· 1 shared H. M. Itkonen· 1 shared M. Loda· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperCancer Biology

A. Gondane

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 7, 2021

Compromised CDK12 activity causes dependency on the non-essential spliceosome components

S. Pallasaho, A. Gondane, D. Duveau…·H. M. Itkonen

This study shows that compromised CDK12 activity in prostate cancer cells leads to addiction to non-essential spliceosome components and lower DNA methylation, suggesting potential therapeutic targets.

DOI 10.1101/2021.12.07.470703

humanbulk RNA-seq

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