A Genetically Encoded BRET-based SARS-CoV-2 Mpro Protease Activity Sensor
A. M. Geethakumari, W. S. Ahmed, S. H. Rasool, A. H. Fatima, S. M. N. Uddin, M. H. Aouida, K. H. Biswas
This paper develops BRET-based sensors to detect SARS-CoV-2 Mpro protease activity in live cells and in vitro, showing improved sensitivity and specificity over existing methods.
bioRxiv · Jan 31, 2022Biophysics