Author

A. H. Kachroo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:yeast· 1

Frequent Co-Authors

E. M. Marcotte· 2 shared J. M. Laurent· 2 shared A. I. Teufel· 1 shared C. O. Wilke· 1 shared M. M. Johnson· 1 shared R. K. Garge· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersEvolutionary Biology

E. M. Marcotte

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2 papers

Recent·Most cited

Systematic humanization of the yeast cytoskeleton discerns functionally replaceable from divergent human genes

R. K. Garge, J. M. Laurent, A. H. Kachroo, E. M. Marcotte

The paper humanizes yeast cytoskeletal genes with human duplicates to assess functional redundancy and divergence, finding only a few human genes can replace yeast orthologs in essential functions.

bioRxiv · Dec 16, 2019Evolutionary Biology

The many nuanced evolutionary consequences of duplicated genes

A. I. Teufel, M. M. Johnson, J. M. Laurent, A. H. Kachroo, E. M. Marcotte, C. O. Wilke

This study investigates how gene duplication affects the evolution of interacting proteins, finding that duplicated genes can drive unexpected functional changes in their partners through dosage imbalance.

bioRxiv · Jul 10, 2018Evolutionary Biology