MicrobiologybioRxivPreprint
Hypoxia-inducible-factors differentially contribute to clinical disease and the control of viral replication during RSV infection
D. R. Morris, Y. Qu, A. Haas de Mello…·A. Casola
This study investigates the differential roles of HIF-1 and HIF-2 inhibitors in RSV infection, finding that HIF-1 inhibition worsens disease but reduces viral replication, while HIF-2 inhibition improves clinical outcomes and reduces viral load.
DOI 10.1101/2023.08.15.553422