Leukotriene B4 licenses inflammasome activation to enhance skin host defense
A. C. G. Salina, S. Brandt, N. Klopfenstein, A. Blackman, N. Byers-Glosson, C. Brodskyn, N. M. Tavares, I. B. Santos Da Silva, A. I. Medeiros, C. H. Serezani
This study shows LTB4 enhances inflammasome assembly and IL-1β production, supporting skin host defense and suggesting therapeutic applications.
bioRxiv · Feb 3, 2020Immunology