Author

C. H. Serezani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Blackman· 1 shared A. C. G. Salina· 1 shared A. Eastman· 1 shared A. Hasty· 1 shared A. I. Medeiros· 1 shared A. Pineros· 1 shared B. Jacobsson· 1 shared C. Brodskyn· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. Blackman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Hyperglycemia increases the severity of Staphylococcus aureus osteomyelitis and influences bacterial genes required for survival in bone.

C. E. Butrico, N. B. Klopfenstein, E. R. Green, J. R. Johnson, S. H. Peck, C. Ibberson, C. H. Serezani, J. E. Cassat

This study shows hyperglycemia worsens Staphylococcus aureus osteomyelitis and identifies genes critical for bacterial survival in high glucose environments.

bioRxiv · Nov 30, 2022 · PreprintMicrobiology

Macrophage-derived miR-21 drives overwhelming glycolytic and inflammatory response during sepsis via repression of the PGE2/IL-10 axis.

P. Melo, A. Pineros, C. H. Serezani

This study shows that macrophage-derived miR-21 promotes sepsis by repressing the PGE2/IL-10 axis, leading to increased glycolysis and inflammation.

bioRxiv · May 9, 2020Immunology

Leukotriene B4 licenses inflammasome activation to enhance skin host defense

A. C. G. Salina, S. Brandt, N. Klopfenstein, A. Blackman, N. Byers-Glosson, C. Brodskyn, N. M. Tavares, I. B. Santos Da Silva, A. I. Medeiros, C. H. Serezani

This study shows LTB4 enhances inflammasome assembly and IL-1β production, supporting skin host defense and suggesting therapeutic applications.

bioRxiv · Feb 3, 2020Immunology

Palmitate induces apoptotic cell death and inflammasome activation in human placental macrophages

L. Rogers, C. H. Serezani, A. Eastman, A. Hasty, L. Englund-Ogge, B. Jacobsson, K. Vickers, D. M. Aronoff

This study shows that palmitate induces NLRP3 inflammasome activation and apoptosis in human placental macrophages, while glucose and insulin do not contribute to these effects.

bioRxiv · Oct 10, 2019Immunology