Doublecortin and JIP3 are neural-specific counteracting regulators of dynein-mediated retrograde trafficking
L. Rao, P. Li, X. Liu, Q. Wang, A. I. Son, A. Gennerich, J. Shih-Hwa Liu, X. Fu
This study identifies DCX and JIP3 as neural-specific regulators that counteract each other in dynein-mediated retrograde trafficking by modulating dynein-microtubule binding and motor complex composition.
bioRxiv · Aug 10, 2022 · PreprintCell Biology