B1a B cells require autophagy for metabolic homeostasis and self-renewal
A. J. Clarke, T. Riffelmacher, D. Braas, R. J. Cornall, A. K. Simon
This study shows B1a B cells rely on autophagy for metabolic homeostasis and self-renewal, with Atg7 deletion causing their loss due to metabolic dysregulation and mitochondrial dysfunction.
bioRxiv · Dec 28, 2017Immunology