A. J. Gibson

M. bovis PPD Enhances Respiratory Bioenergetics of Human vs. Bovine Macrophages

This study compares the respiratory bioenergetics of human and bovine macrophages in response to M. bovis PPD and other TLR ligands, finding species-specific metabolic changes only in human macrophages.

Characterisation of the bovine C-type lectin receptor Mincle and potential evidence for an endogenous ligand

This study characterizes bovine Mincle, showing structural and functional similarity to human Mincle, with potential endogenous ligand recognition.

Defining the genes required for survival of Mycobacterium bovis in the bovine host offers novel insights into the genetic basis of survival of pathogenic mycobacteria

This study identifies genes required for Mycobacterium bovis survival in cattle using transposon insertion sequencing, revealing both known and novel virulence factors.

Probing differences in gene essentiality between the human and animal adapted lineages of the Mycobacterium tuberculosis complex using TnSeq

This study compares gene essentiality between Mycobacterium bovis and Mycobacterium tuberculosis using transposon sequencing and CRISPRi, finding species-specific differences in essential genes and their functional roles.