Author

A. J. McKenzie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. K. Howe· 2 shared K. V. Svec· 2 shared H. Naughton· 1 shared S. R. Hicks· 1 shared T. F. Williams· 1 shared Z. L. Edmunds· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

A. K. Howe

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2 papers

Recent·Most cited

Protein Kinase A activity is regulated by actomyosin contractility during cell migration and is required for durotaxis

A. J. McKenzie, T. F. Williams, K. V. Svec, A. K. Howe

This study shows PKA activity is regulated by actomyosin contractility during cell migration and is necessary for durotaxis.

bioRxiv · Aug 15, 2018Cell Biology

The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

A. J. McKenzie, S. R. Hicks, K. V. Svec, H. Naughton, Z. L. Edmunds, A. K. Howe

This study shows that matrix stiffness affects ovarian cancer cell behavior, including migration and spheroid disaggregation, through mechanotransduction pathways.

bioRxiv · Dec 21, 2017Cell Biology