Myosin II Tension Sensors Visualize Force Generation within the Actin Cytoskeleton in Living Cells
R. G. Hart, D. Kota, F. Li, D. Ramallo, A. J. Price, K. L. Otterpohl, S. J. Smith, A. R. Dunn, J. Liu, I. Chandrasekar
The paper introduces a FRET-based tension sensor to measure forces generated by NMIIB in living cells, revealing spatial and temporal heterogeneity in cytoskeletal forces.
bioRxiv · May 2, 2019Cell Biology