Legumain is a paracrine regulator of osteoblast differentiation and mediates the inhibitory effect of TGF-β1 on osteoblast maturation
K. M. Forbord, N. N. Lunde, T. Bosnjak-Olsen, H. T. Johansen, R. Solberg, A. Jafari
This study identifies legumain as a paracrine factor mediating TGF-β1's inhibitory effect on osteoblast maturation through increased secretion and internalization.
bioRxiv · Apr 12, 2024Cell Biology