3D single molecule localization microscopy reveals the topography of the immunological synapse at isotropic precision below 15 nm
L. Velas, M. Brameshuber, J. B. Huppa, E. Kurz, M. Dustin, P. Zelger, A. Jesacher, G. J. Schuetz
This study uses 3D-SMLM to measure the cleft size in immunological synapses between T-cells and lipid bilayers, finding distances of 18-31 nm.
bioRxiv · Aug 9, 2021Biophysics