Amount of antigen, T follicular helper cells and quality of seeder cells shape the diversity of germinal center B cells
A. K. Garg, T. Mitra, M. Schips, A. Bandyopadhyay, M. Meyer-Hermann
This study uses an agent-based model to show that antigen availability, T follicular helper cells, and high-affinity founder cells influence germinal center B cell diversity and affinity maturation.
bioRxiv · Oct 26, 2022 · PreprintImmunology