Author

A. K. Hatstat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

D. G. McCafferty· 3 shared B. Quan· 1 shared H. D. Ahrendt· 1 shared L. Mayne· 1 shared M. A. Moseley· 1 shared M. Bailey· 1 shared M. C. Fitzgerald· 1 shared M. C. Reinhart· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

D. G. McCafferty

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Author profile →

3 papers

Recent·Most cited

Chemoproteomic-enabled characterization of small GTPase Rab1a as a target of an N-arylbenzdiimidazole ligand's rescue of Parkinson's-associated cell toxicity

A. K. Hatstat, B. Quan, M. Bailey, M. C. Fitzgerald, M. C. Reinhart, D. G. McCafferty

This paper identifies Rab1a as a target of the compound NAB2, which rescues Parkinson's-associated cell toxicity by restoring ER-to-Golgi trafficking.

bioRxiv · May 5, 2021Biochemistry

Bioinformatic and computational analysis reveals the prevalence and nature of PY motif-mediated protein-protein interactions in the Nedd4 family of ubiquitin ligases

A. K. Hatstat, M. D. Pupi, D. G. McCafferty

The paper develops a tool to analyze PY motifs in Nedd4 family ligases, finding that half of their interactions are PY-motif mediated, with PPxY motifs being more prevalent and disordered.

bioRxiv · Nov 12, 2020 · PreprintBiochemistry

Characterization of small molecule induced changes in Parkinson's-related trafficking via the Nedd4 ubiquitin signaling cascade

A. K. Hatstat, H. D. Ahrendt, M. W. Foster, L. Mayne, M. A. Moseley, S. W. Englander, D. G. McCafferty

The paper investigates how NAB2 affects Nedd4 ubiquitin ligase activity and substrate specificity in Parkinson's-related trafficking defects.

bioRxiv · Jun 1, 2020Biochemistry