Author

S. W. Englander

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

L. Mayne· 2 shared Z.-Y. Kan· 2 shared A. K. Hatstat· 1 shared A. Sommer· 1 shared B. A. Garcia· 1 shared B. E. Black· 1 shared C. Vitali· 1 shared D. G. McCafferty· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiochemistry

L. Mayne

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Author profile →

4 papers

Recent·Most cited

ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

F. Shi, J. M. Mendrola, J. B. Sheetz, N. Wu, A. Sommer, K. F. Speer, J. N. Noordermeer, Z.-Y. Kan, K. Perry, S. W. Englander, S. E. Stayrook, L. G. Fradkin, M. A. Lemmon

The paper presents crystal structures of Drosophila ROR and RYK orthologs, revealing distinct WNT-recognition mechanisms through their extracellular domains.

bioRxiv · Apr 29, 2021Biochemistry

ApoC-III helical structure determines its ability to bind plasma lipoproteins and inhibit Lipoprotein Lipase-mediated triglyceride lipolysis.

C. Vitali, S. Stankov, S. A. Khetarpal, J. Millar, L. Mayne, S. W. Englander, N. J. Hand, S. Lund-Katz, M. C. Phillips, D. J. Rader

This study investigates how structural changes in apoC-III affect its interaction with lipoproteins and LPL activity, revealing that hydrophilic-lipophilic properties of alpha helices modulate triglyceride levels.

bioRxiv · Jul 2, 2020 · PreprintBiochemistry

Characterization of small molecule induced changes in Parkinson's-related trafficking via the Nedd4 ubiquitin signaling cascade

A. K. Hatstat, H. D. Ahrendt, M. W. Foster, L. Mayne, M. A. Moseley, S. W. Englander, D. G. McCafferty

The paper investigates how NAB2 affects Nedd4 ubiquitin ligase activity and substrate specificity in Parkinson's-related trafficking defects.

bioRxiv · Jun 1, 2020Biochemistry

Hydrogen-deuterium exchange coupled to top- and middle-down mass spectrometry enables high-resolution measurements of histone tail dynamics before and after nucleosome assembly

K. R. Karch, M. Coradin, L. Zandarashvili, Z.-Y. Kan, M. Gerace, S. W. Englander, B. E. Black, B. A. Garcia

This paper uses HDX-MS/MS with ETD to study histone tail dynamics before and after nucleosome assembly, achieving high-resolution deuterium localization.

bioRxiv · Apr 28, 2018Biochemistry