Author

L. Mayne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1

Frequent Co-Authors

S. W. Englander· 2 shared A. Ali· 1 shared A. K. Hatstat· 1 shared B. E. Black· 1 shared C. Vitali· 1 shared D. G. McCafferty· 1 shared D. J. Rader· 1 shared E. Niedzialkowska· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

S. W. Englander

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Author profile →

3 papers

Recent·Most cited

Structural Basis for the Phase Separation of the Chromosome Passenger Complex

N. W. Bryan, A. Ali, E. Niedzialkowska, L. Mayne, P. T. Stukenberg, B. E. Black

The paper identifies contact regions in the chromosome passenger complex (CPC) that drive phase separation using hydrogen/deuterium-exchange mass spectrometry.

bioRxiv · May 22, 2023Biochemistry

ApoC-III helical structure determines its ability to bind plasma lipoproteins and inhibit Lipoprotein Lipase-mediated triglyceride lipolysis.

C. Vitali, S. Stankov, S. A. Khetarpal, J. Millar, L. Mayne, S. W. Englander, N. J. Hand, S. Lund-Katz, M. C. Phillips, D. J. Rader

This study investigates how structural changes in apoC-III affect its interaction with lipoproteins and LPL activity, revealing that hydrophilic-lipophilic properties of alpha helices modulate triglyceride levels.

bioRxiv · Jul 2, 2020 · PreprintBiochemistry

Characterization of small molecule induced changes in Parkinson's-related trafficking via the Nedd4 ubiquitin signaling cascade

A. K. Hatstat, H. D. Ahrendt, M. W. Foster, L. Mayne, M. A. Moseley, S. W. Englander, D. G. McCafferty

The paper investigates how NAB2 affects Nedd4 ubiquitin ligase activity and substrate specificity in Parkinson's-related trafficking defects.

bioRxiv · Jun 1, 2020Biochemistry