Author

A. K. Ottens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

H. Adcox· 1 shared J. A. Carlyon· 1 shared J. R. Hunt· 1 shared K. G. Rodino· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperMicrobiology

H. Adcox

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1 paper

Recent·Most cited

Orientia tsutsugamushi Ank5 directs ubiquitination and proteasomal degradation of NLRC5 to inhibit major histocompatibility complex class I expression

H. Adcox, J. R. Hunt, K. G. Rodino, A. K. Ottens, J. A. Carlyon

This study identifies Ank5 as a bacterial effector that degrades NLRC5 to inhibit MHC class I expression, revealing a mechanism for immune evasion by Orientia tsutsugamushi.

bioRxiv · Dec 4, 2023 · PreprintMicrobiology