Cold-induced loss of interaction with HSC70 triggers inflammasome activity of familial cold autoinflammatory syndrome-causing mutants of NLRP3
A. K. Raghawan, R. Ramaswamy, G. Swarup
This study shows that cold-induced loss of NLRP3-HSC70 interaction triggers inflammasome activity in FCAS1-causing NLRP3 mutants.
bioRxiv · Nov 16, 2022Immunology