Super-resolved polarisation-enhanced second harmonic generation for direct imaging of nanoscale changes in collagen architecture
P. B. Johnson, A. Karvounis, J. Singh, C. J. Brereton, K. Bourdakos, K. Lunn, J. J. Roberts, D. E. Davies, O. L. Muskens, M. G. Jones, S. Mahajan
This paper introduces a super-resolution SHG technique that achieves nanoscale imaging of collagen architecture without fluorescent labels, revealing previously unobservable structural changes.
bioRxiv · Feb 7, 2020Biophysics