Author

D. E. Davies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:imputation· 1

Frequent Co-Authors

C. J. Brereton· 3 shared M. G. Jones· 2 shared P. B. JOHNSON· 2 shared R. A. Ridley· 2 shared S. Mahajan· 2 shared A. Alzetani· 1 shared A. Bhaskar· 1 shared A. Fabre· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBiophysics

C. J. Brereton

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis

C. J. Brereton, L. Yao, Y. Zhou, M. Vukmirovic, J. A. Bell, R. A. Ridley, E. Davies, L. S. N. Dean, O. G. Andriotis, F. Conforti, S. Mohammed, T. Wallis, A. Tavassoli, R. Ewing, A. Alzetani, , M. Jones

This study shows that pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis by promoting bone-type cross-linking and increasing tissue stiffness.

bioRxiv · May 11, 2021Cell Biology

Label-free and Multimodal Second Harmonic Generation Light Sheet Microscopy

N. Hanrahan, S. I. R. Lane, P. B. JOHNSON, K. N. Bourdakos, C. J. Brereton, R. A. Ridley, E. R. Davies, N. A. Hosny, G. Spickermann, R. Forster, G. Malcolm, D. E. Davies, M. G. Jones, S. Mahajan

This paper demonstrates a label-free SHG-LSM technique for 3D imaging of collagen and other harmonophores, combining SHG with light sheet microscopy for multimodal imaging.

bioRxiv · Sep 7, 2020 · PreprintBiophysics

Super-resolved polarisation-enhanced second harmonic generation for direct imaging of nanoscale changes in collagen architecture

P. B. Johnson, A. Karvounis, J. Singh, C. J. Brereton, K. Bourdakos, K. Lunn, J. J. Roberts, D. E. Davies, O. L. Muskens, M. G. Jones, S. Mahajan

This paper introduces a super-resolution SHG technique that achieves nanoscale imaging of collagen architecture without fluorescent labels, revealing previously unobservable structural changes.

bioRxiv · Feb 7, 2020Biophysics