A. Keskin

A bacteria-derived tail anchor localizes to peroxisomes in yeast and mammalian cells

The paper shows that a bacteria-derived tail anchor from E. coli localizes to peroxisomes in yeast and mammalian cells, suggesting its utility in studying peroxisomal targeting mechanisms.

Bacterial tail anchors can target to the mitochondrial outer membrane

The paper investigates whether bacterial tail anchors can target to the mitochondrial outer membrane in yeast, finding that specific bacterial TAs are localized to and inserted in the mitochondrial outer membrane.

Deep mutational scanning reveals characteristics important for targeting of the tail-anchored protein Fis1

The paper uses deep mutational scanning to analyze the tail-anchored domain of Fis1p, revealing that positively charged residues are critical for mitochondrial targeting and that TA length does not dictate organelle specificity.