Author

A. Koeberle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Assay:bulk RNA-seq· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

O. Werz· 2 shared A. Dakhovnik· 1 shared A. Gollowitzer· 1 shared A. Lupp· 1 shared A. Martirosyan· 1 shared A. Nair· 1 shared A. Ori· 1 shared A. Zarrelli· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

O. Werz

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2 papers

Recent·Most cited

Silybin A from Silybum marianum reprograms lipid metabolism to induce a cell fate-dependent class switch from triglycerides to phospholipids

S. C. Koeberle, M. Thuermer, M. Werner, J. Grander, L. Hofer, A. Gollowitzer, F. Su, L. Le Xuan, F. J. Benscheid, E. Bonyadi Rad, A. Zarrelli, G. Di Fabio, O. Werz, V. Romanucci, A. Lupp, A. Koeberle

This study identifies silybin A's role in reprogramming lipid metabolism to shift from triglycerides to phospholipids in liver cells, with implications for liver protection.

bioRxiv · Apr 9, 2024 · PreprintPharmacology & Toxicology

Late life metformin treatment limits cell survival and shortens lifespan by triggering an aging-associated failure of energy metabolism.

L. Espada, A. Dakhovnik, P. S. Chaudhari, A. Martirosyan, L. Miek, T. Poliezhaieva, Y. Schaub, A. Nair, N. Doering, N. Rahnis, O. Werz, A. Koeberle, J. Kirkpatrick, A. Ori, M. Ermolaeva

This study shows that late-life metformin treatment reduces cell survival and lifespan by impairing energy metabolism, contrasting its beneficial effects in early life.

bioRxiv · Dec 3, 2019 · PreprintPhysiology