ATP13A4 upregulation drives the elevated polyamine transport system in the breast cancer cell line MCF7
S. van Veen, A. Kourti, E. Ausloos, J. Van Asselberghs, C. Van den Haute, V. Baekelandt, J. Eggermont, P. Vangheluwe
This study identifies ATP13A4 as a key polyamine transporter upregulated in breast cancer cells, contributing to increased polyamine uptake and sensitivity to polyamine toxicity.
bioRxiv · Mar 31, 2023 · PreprintCell Biology