Author

V. Baekelandt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. Van den Haute· 4 shared P. Vangheluwe· 3 shared J. Eggermont· 2 shared S. Martin· 2 shared A. A. Hicks· 1 shared A. Kourti· 1 shared A. Picard· 1 shared B. Liu· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersCell Biology

C. Van den Haute

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Author profile →

5 papers

Recent·Most cited

ATP13A3 Variants Promote Pulmonary Arterial Hypertension by Disrupting Polyamine Transport

B. Liu, M. Azfar, E. Legchenko, J. A. West, S. Martin, C. Van den Haute, V. Baekelandt, J. Wharton, L. Howard, M. Wilkins, P. Vangheluwe, N. W. Morrell, P. D. Upton

This study identifies ATP13A3 as a polyamine transporter whose deficiency leads to endothelial dysfunction and pulmonary arterial hypertension.

bioRxiv · Aug 29, 2023 · PreprintCell Biology

The lipid flippase ATP10B enables cellular lipid uptake under stress conditions

R. Wouters, I. Beletchi, C. Van den Haute, V. Baekelandt, S. Martin, J. Eggermont, P. Vangheluwe

This study shows that ATP10B, a lipid flippase, enhances cellular phosphatidylcholine uptake under stress conditions like rotenone treatment.

bioRxiv · Jun 1, 2023Cell Biology

ATP13A4 upregulation drives the elevated polyamine transport system in the breast cancer cell line MCF7

S. van Veen, A. Kourti, E. Ausloos, J. Van Asselberghs, C. Van den Haute, V. Baekelandt, J. Eggermont, P. Vangheluwe

This study identifies ATP13A4 as a key polyamine transporter upregulated in breast cancer cells, contributing to increased polyamine uptake and sensitivity to polyamine toxicity.

bioRxiv · Mar 31, 2023 · PreprintCell Biology

Label-free imaging of membrane potentials by intramembrane field modulation, assessed by Second Harmonic Generation Microscopy

Y. de Coene, S. Jooken, O. Deschaume, V. Van Steenbergen, P. Vanden Berghe, C. Van den Haute, V. Baekelandt, G. Callewaert, S. Van Cleuvenbergen, T. Verbiest, C. Bartic, K. Clays

This study demonstrates that second harmonic generation (SHG) from live cells is sensitive to membrane potential changes, offering a label-free method for measuring electrical activity.

bioRxiv · May 28, 2021Biophysics

Kinase inhibition of G2019S-LRRK2 restores autolysosome formation and function to reduce endogenous alpha-synuclein intracellular inclusions

J. Obergasteiger, G. Frapporti, G. Lamonaca, S. Pizzi, A. Picard, F. Pischedda, G. Piccoli, E. Lobbestael, V. Baekelandt, A. A. Hicks, C. Corti, P. P. Pramstaller, M. Volta

This study investigates how G2019S-LRRK2 mutation disrupts autophagy-lysosome pathway function and leads to alpha-synuclein accumulation, showing kinase inhibition can restore pathway function and reduce inclusions.

bioRxiv · Jul 20, 2019Cell Biology