Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR
A. L. Herlinger, G. L. Michaelsen, M. Sinigaglia, L. Fratini, G. N. Debom, E. Braganhol, C. B. de Farias, A. L. Brunetto, A. T. Brunetto, M. d. C. Jaeger, R. Roesler
This study shows rosmarinic acid reduces proliferation and stemness in medulloblastoma cells by targeting HDAC1, EGFR, and ERK signaling, and increasing p21 expression.
bioRxiv · Aug 10, 2023Cancer Biology