Determination of secretory granule maturation times in pancreatic islet beta-cells by serial block face scanning electron microscopy
A. Rao, E. L. McBride, G. Zhang, T. Cai, A. L. Notkins, M. A. Aronova, R. D. Leapman
The paper uses SBEM to determine secretory granule maturation times in mouse pancreatic beta-cells, finding immature granules remain in their state for about 2 hours before transforming.
bioRxiv · Dec 5, 2019Biophysics