Author

A. Ledda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:Bayesian inference· 1 Research Focus:clustering· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

X. Didelot· 3 shared B. Cherian· 1 shared C. Rosmarin· 1 shared D. Barry· 1 shared D. Helekal· 1 shared D. Wareham· 1 shared D. Wyllie· 1 shared E. Jauneikaite· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersEvolutionary Biology

X. Didelot

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3 papers

Recent·Most cited

The bounded coalescent model: conditioning a genealogy on a minimum root date

J. Carson, A. Ledda, L. Ferretti, M. Keeling, X. Didelot

The paper introduces a new algorithm for simulating the bounded coalescent model directly, showing improved computational efficiency and providing methods to calculate probabilities under this model.

bioRxiv · Jan 4, 2022Evolutionary Biology

Bayesian inference of clonal expansions in a dated phylogeny

D. Helekal, A. Ledda, E. Volz, D. Wyllie, X. Didelot

The paper develops a Bayesian model to infer clonal expansions in phylogenies and applies it to simulated and real datasets.

bioRxiv · Jul 1, 2021Evolutionary Biology

Hospital outbreak of carbapenem-resistant Enterobacteriales associated with an OXA-48 plasmid carried mostly by Escherichia coli ST399

A. Ledda, M. Cummins, L. P. Shaw, E. Jauneikaite, K. Cole, F. Lasalle, D. Barry, C. Rosmarin, S. Anaraki, D. Wareham, N. Stoesser, J. Paul, R. Manuel, B. Cherian, X. Didelot

The paper investigates a hospital outbreak of carbapenem-resistant Enterobacteriales, identifying an OXA-48 plasmid in E. coli ST399 as the main driver, with evidence of plasmid conjugation and clonal expansion.

bioRxiv · Jun 15, 2020Evolutionary Biology