Author

D. Wyllie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:whole-genome sequencing· 3 Organism:human· 2 Research Focus:variant calling· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. W. Crook· 2 shared E. Robinson· 2 shared G. Smith· 2 shared N. D. Sanderson· 2 shared X. Didelot· 2 shared A. Ledda· 1 shared A. S. Walker· 1 shared B. C. Young· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

D. W. Crook

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Inference of infectious disease transmission using multiple genomes per host

J. Carson, M. Keeling, D. Wyllie, P. Ribeca, X. Didelot

This paper introduces a method to infer infectious disease transmission networks using multiple genomes per host, showing improved accuracy with more genomes and applying it to real outbreaks.

bioRxiv · Jul 28, 2023 · PreprintMicrobiology

Bayesian inference of clonal expansions in a dated phylogeny

D. Helekal, A. Ledda, E. Volz, D. Wyllie, X. Didelot

The paper develops a Bayesian model to infer clonal expansions in phylogenies and applies it to simulated and real datasets.

bioRxiv · Jul 1, 2021Evolutionary Biology

Panton-Valentine leukocidin is the key determinant of Staphylococcus aureus pyomyositis in a bacterial genome-wide association study

B. C. Young, S. G. Earle, S. Soeng, P. Sar, V. Kumar, S. Hor, V. Sar, R. Bousfield, N. D. Sanderson, L. Barker, N. Stoesser, K. R. Emary, C. M. Parry, E. K. Nickerson, P. Turner, , C. E. Moore

bioRxiv · Sep 29, 2018 · PreprintMicrobiology

A quantitative evaluation of MIRU-VNTR typing against whole-genome sequencing for identifying Mycobacterium tuberculosis transmission: A prospective observational cohort study

D. Wyllie, J. Davidson, T. Walker, P. Rathod, T. Peto, E. Robinson, D. W. Crook, G. Smith, C. Campbell

This study evaluates MIRU-VNTR typing against whole-genome sequencing to identify Mycobacterium tuberculosis transmission, finding low predictive value of MIRU-VNTR and lineage-specific performance.

bioRxiv · Jan 24, 2018Microbiology

Control of artefactual variation in reported inter-sample relatedness during clinical use of a Mycobacterium tuberculosis sequencing pipeline

D. Wyllie, N. D. Sanderson, R. Myers, T. E. Peto, E. Robinson, D. W. Crook, G. Smith, A. S. Walker

The paper identifies genomic regions in Mycobacterium tuberculosis that contribute to artefactual variation in bacterial similarity searches and proposes a method to reduce such variation.

bioRxiv · Jan 23, 2018Microbiology