MicrobiologybioRxiv
Characterization of a novel intratracheal aerosol challenge model of Brucella melitensis in guinea pigs
M. Hensel, D. G. Garcia-Gonzalez, S. P. Chaki…·A. M. Arenas-Gamboa
This paper establishes an intratracheal aerosol challenge model in guinea pigs to study Brucella melitensis infection, showing dose-dependent colonization and disease symptoms similar to human brucellosis.
DOI 10.1371/journal.pone.0212457