Author

A. M. Brzozowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Marek· 1 shared C. M. Viola· 1 shared H. T. Jenkins· 1 shared I. Selicharova· 1 shared J. Jiracek· 1 shared J. Kaminsky· 1 shared L. Mrazkova· 1 shared L. Zakova· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Marek

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2 papers

Recent·Most cited

Structural Conservation of Insulin/IGF Signalling Axis at the Insulin Receptors Level in Drosophila and Humans

C. M. Viola, O. Frittmann, H. T. Jenkins, T. Shafi, P. De Meyts, A. M. Brzozowski

This study presents the cryoEM structure of the Drosophila insulin receptor (dmIR) complex with DILP5, showing structural homology to human IRs and dmIR-specific features.

bioRxiv · Feb 17, 2023 · PreprintBiochemistry

Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2

P. Potalitsyn, L. Mrazkova, I. Selicharova, M. Tencerova, M. Ferencakova, M. Chrudinova, A. M. Brzozowski, A. Marek, J. Kaminsky, J. Jiracek, L. Zakova

The paper compares the mitogenic activity of different IGF2 proforms and finds that non-glycosylated pro-IGF2(156) and big-IGF2(104) have higher proliferative properties than native IGF2.

bioRxiv · Jan 16, 2023Biochemistry