Srsf2P95H/+ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia like disease in mice.
J. J. Xu, A. M. Chalk, M. Wall, W. Y. Langdon, M. F. Smeets, C. R. Walkley
This paper shows that Srsf2P95H/+ and Tet2 loss cooperate in mice to cause a CMML-like disease with myeloid bias and monocytosis.
bioRxiv · Jun 21, 2022Cancer Biology