Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells and protects against liver fibrosis
K. Du, S.-H. Oh, T. Sun, W.-H. Yang, J.-T. A. Chi, A. M. Diehl
This study shows that inhibiting xCT/SLC7A11 induces ferroptosis in myofibroblastic hepatic stellate cells, reducing liver fibrosis without worsening liver injury.
bioRxiv · Dec 23, 2019 · PreprintCell Biology