Longitudinal dynamics of human B-cell response at single-cell level in response to Tdap vaccination
I. Khatri, A. M. Diks, E. B. van den Akker, L. E. M. Oosten, J. J. Zwaginga, M. J. T. Reinders, J. J. M. van Dongen, M. A. Berkowska
This study tracks longitudinal B-cell responses to Tdap vaccination using single-cell transcriptomics and BCR repertoires, identifying clonal expansion, class switching, and antigen-specific BCRs.
bioRxiv · Oct 8, 2021Immunology