Author

J. J. M. van Dongen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 5 Organism:human· 5 Approach:statistical model· 3 Research Focus:clustering· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:variant calling· 2

Frequent Co-Authors

E. B. van den Akker· 3 shared I. Khatri· 3 shared C. Teodosio· 2 shared M. A. Berkowska· 2 shared M. J. T. Reinders· 2 shared A. J. van der Sluijs-Gelling· 1 shared A. M. Diks· 1 shared F. A. Moretti· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

E. B. van den Akker

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ImmunologybioRxivJun 30, 2023

Autoantibody subclass predominance is not driven by aberrant class switching or impaired B cell development

L. M. Paardekooper, Y. E. Fillie-Grijpma, A. J. van der Sluijs-Gelling…·M. G. Huijbers

The paper investigates why IgG4 autoantibodies predominate in certain autoimmune diseases and finds that B cell development is normal, suggesting antigen-driven subclass predominance rather than B cell dysfunction.

DOI 10.1016/j.clim.2023.109817

humanflow cytometry

𝕏 PostBluesky

ImmunologybioRxivFeb 18, 2022

Single-cell immune profiling reveals novel thymus-seeding populations, T cell commitment, and multi-lineage development in the human thymus

M. Cordes, K. Cante-Barrett, E. B. van den Akker…·F. J. T. Staal

The paper uses single-cell techniques to study human T cell development, identifying thymus-seeding progenitors and multi-lineage potential in the human thymus.

DOI 10.1126/sciimmunol.ade0182

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivOct 8, 2021

Longitudinal dynamics of human B-cell response at single-cell level in response to Tdap vaccination

I. Khatri, A. M. Diks, E. B. van den Akker…·M. A. Berkowska

This study tracks longitudinal B-cell responses to Tdap vaccination using single-cell transcriptomics and BCR repertoires, identifying clonal expansion, class switching, and antigen-specific BCRs.

DOI 10.3390/vaccines9111352

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivDec 23, 2020

pmTR database: population matched (PM) germline allelic variants of T-cell receptor (TR) loci

J. Dekker, J. J. M. van Dongen, M. Reinders, I. Khatri

The paper introduces the pmTR database, which provides population-specific germline T-cell receptor alleles from 26 human populations, enhancing research on population-specific immune responses.

DOI 10.1038/s41435-022-00171-x

humanDNA methylation

𝕏 PostBluesky

ImmunologybioRxivApr 9, 2020

Population matched (PM) germline allelic variants of immunoglobulin (IG) loci: New pmIG database to better understand IG repertoire and selection processes in disease and vaccination

I. Khatri, M. A. Berkowska, E. B. van den Akker…·J. J. M. van Dongen

The paper presents a new population-matched immunoglobulin (pmIG) database containing accurate germline alleles from 26 human populations, revealing evolutionary patterns and diversity in IG loci.

DOI 10.1038/s41435-021-00143-7

humanDNA methylation

𝕏 PostBluesky