Collagen Density Modulates the Immunosuppressive Functions of Tumor-Associated Macrophages
A. M. H. Larsen, D. E. Kuczek, A. Kalvisa, M. Siersbaek, M.-L. Thorseth, A. Z. Johansen, M. Carretta, L. Groentved, O. Vang, D. H. Madsen
This study shows that high collagen density promotes immunosuppressive functions in tumor-associated macrophages, potentially reducing immunotherapy efficacy and linking to poor prognosis.
bioRxiv · Jun 28, 2019Immunology