Author

D. H. Madsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Kalvisa· 2 shared D. E. Kuczek· 2 shared M. Carretta· 2 shared A. M. Carnaz Simoes· 1 shared A. M. H. Larsen· 1 shared A. M. Hvid Larsen· 1 shared A. Roslind· 1 shared A. Z. Johansen· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. Kalvisa

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2 papers

Recent·Most cited

Collagen Density Modulates the Immunosuppressive Functions of Tumor-Associated Macrophages

A. M. H. Larsen, D. E. Kuczek, A. Kalvisa, M. Siersbaek, M.-L. Thorseth, A. Z. Johansen, M. Carretta, L. Groentved, O. Vang, D. H. Madsen

This study shows that high collagen density promotes immunosuppressive functions in tumor-associated macrophages, potentially reducing immunotherapy efficacy and linking to poor prognosis.

bioRxiv · Jun 28, 2019Immunology

Collagen density regulates the activity of tumor-infiltrating T cells

D. E. Kuczek, A. M. Hvid Larsen, M. Carretta, A. Kalvisa, M. S. Siersbaek, A. M. Carnaz Simoes, A. Roslind, L. H. Engelholm, M. Donia, I. M. Svane, P. t. Straten, L. Grontved, D. H. Madsen

This study shows that high collagen density in tumors reduces T cell proliferation and cytotoxicity, while increasing regulatory T cells, suggesting collagen density modulates T cell function in the tumor microenvironment.

bioRxiv · Dec 12, 2018Immunology