C. elegans XMAP215/ZYG-9 and TACC/TAC-1 act at multiple times throughout oocyte meiotic spindle assembly to promote both the coalescence of pole foci into a bipolar structure and the stability of coalesced poles during oocyte meiotic cell division
This study identifies multiple temporally distinct roles of ZYG-9/TAC-1 in C. elegans oocyte meiotic spindle assembly, promoting pole coalescence and stability during both meiosis I and II.
bioRxiv · Aug 2, 2022 · PreprintCell Biology