Author

A. M. Hounslow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

M. P. Williamson· 2 shared , R. F. W. Jackson· 1 shared D. Sangar· 1 shared E. Risse· 1 shared J. Bieschke· 1 shared J. Collinge· 1 shared J. P. Waltho· 1 shared L. L. P. Hosszu· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

M. P. Williamson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of the first β-strand of human prion protein generates an aggregation-competent partially "open" form

L. L. P. Hosszu, D. Sangar, M. Batchelor, E. Risse, A. M. Hounslow, J. P. Waltho, J. Collinge, J. Bieschke

This study examines the structural and functional changes in a truncated form of human prion protein lacking a conserved membrane region, showing it forms fibrils more readily than the native form.

bioRxiv · Sep 20, 2022 · PreprintBiophysics

Improved methodology for protein NMR structure calculation using hydrogen bond restraints and ANSURR validation: the SH2 domain of SH2B1

N. J. Fowler, M. F. Albalwi, S. Lee, A. M. Hounslow, M. P. Williamson

The paper improves NMR structure calculation by incorporating hydrogen bond restraints and using ANSURR validation, resulting in more accurate SH2 domain structures.

bioRxiv · Aug 29, 2022Biophysics

31P NMR Spectroscopy Demonstrates Large Amounts of Phosphohistidine in Mammalian Cells

M. V. Makwana, S. van Meurs, A. M. Hounslow, M. P. Williamson, , R. F. W. Jackson, R. Muimo

This paper quantifies phosphohistidine levels in mammalian cells using 31P NMR, finding it to be more abundant than phosphotyrosine but less than phosphoserine/phosphothreonine combined.

bioRxiv · Dec 3, 2020 · PreprintBiochemistry