Mutant p53 triggers a dynamin-1/APPL1 endosome feedback loop that regulates β1 integrin recycling and migration
A. M. Lakoduk, P. Roudot, M. Mettlen, H. M. Grossman, P.-H. Chen, S. L. Schmid
This study identifies a feedback loop involving mutant p53, dynamin-1, and APPL1 endosomes that enhances β1 integrin recycling and cell migration in cancer.
bioRxiv · Sep 5, 2018Cell Biology