P. Roudot

Resolution doubling in light-sheet microscopy via oblique plane structured illumination

This paper demonstrates isotropic resolution doubling in light-sheet microscopy using oblique plane structured illumination, achieving sub-150nm lateral resolution with reduced phototoxicity and faster volumetric imaging.

In vivo profiling of site-specific human cancer cell states in zebrafish

The paper uses zebrafish xenografts and computer vision to study how Ewing Sarcoma cell morphology changes in different sites and under EWSR1-FLI1 expression variations.

u-track 3D: measuring and interrogating dense particle dynamics in three dimensions.

u-track 3D provides a software package for analyzing dense 3D particle dynamics in microscopy data by improving visualization, trajectory validation, and interactive exploration.

Real-Time Multi-Angle Projection Imaging of Biological Dynamics

This paper introduces a projection imaging method that enables real-time, multi-angle visualization of biological processes with reduced data overhead.

Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D

The paper investigates the role of actin-binding proteins in cell spreading on 2D and 3D substrates, finding that Arp2/3-vinculin binding is critical for 3D spreading but not 2D.

Light-sheet microscopy with isotropic, sub-micron resolution and solvent-independent large-scale imaging

This paper introduces ctASLM, a light-sheet microscopy technique with sub-micron isotropic resolution and large-scale imaging, enabling automated cell and subcellular feature detection in cleared tissues.

Augmin-mediated amplification of long-lived spindle microtubules directs plus-ends to kinetochores

The paper shows that Augmin amplifies long-lived microtubules, directing their plus-ends to kinetochores during spindle assembly in human cells.

Universal Light-Sheet Generation with Field Synthesis

This paper introduces Field Synthesis, a theorem that simplifies light-sheet generation for microscopy, enabling high-throughput, multicolor imaging with reduced photobleaching.

Mutant p53 triggers a dynamin-1/APPL1 endosome feedback loop that regulates β1 integrin recycling and migration

This study identifies a feedback loop involving mutant p53, dynamin-1, and APPL1 endosomes that enhances β1 integrin recycling and cell migration in cancer.