Drug-like Fragments Inhibit agr-Mediated Virulence Expression in Staphylococcus aureus
I. F. Bezar, A. A. Mashruwala, J. M. Boyd, A. M. Stock
The paper tests five compound fragments for their ability to inhibit agr-mediated virulence in Staphylococcus aureus, finding three reduce agr-driven transcription and two lower secreted toxins.
bioRxiv · Feb 1, 2019Microbiology