Author

A. A. Mashruwala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:bacteria (other)· 2 Organism:virus· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. Bassler· 2 shared B. L. Bassler· 2 shared A. M. Stock· 1 shared B. Qin· 1 shared C. Fei· 1 shared I. F. Bezar· 1 shared J. M. Boyd· 1 shared J. S. Sun· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

B. Bassler

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Quorum-sensing- and type VI secretion-mediated spatio-temporal cell death drives genetic diversity in Vibrio cholerae

A. A. Mashruwala, B. Qin, B. L. Bassler

This study shows that T6SS-mediated cell death in V. cholerae colonies drives genetic diversity through quorum-sensing-controlled spatio-temporal phases of cell death.

bioRxiv · Aug 9, 2022 · PreprintMicrobiology

Bacterial LomR Induces the Vibriophage VP882 VqmA-Directed Quorum-Sensing Lysogeny-Lysis Transition

J. S. Sun, A. A. Mashruwala, C. Fei, B. Bassler

This paper identifies LomR, OmpX, and OmpT as bacterial proteins that induce phage lysis by triggering quorum-sensing in vibriophages.

bioRxiv · Nov 15, 2021 · PreprintMicrobiology

Secreted Proteases Control the Timing of Aggregative Community Formation in Vibrio cholerae

M. Jemielita, A. A. Mashruwala, J. S. Valastyan, N. Wingreen, B. Bassler

The paper identifies four extracellular proteases that control the timing of void formation and aggregation in Vibrio cholerae, revealing a redundant mechanism for community formation.

bioRxiv · May 25, 2021Microbiology

The Vibrio cholerae quorum-sensing protein VqmA integrates cell density, environmental, and host-derived cues into the control of virulence

A. A. Mashruwala, B. L. Bassler

This study shows VqmA integrates environmental and host cues with quorum sensing to regulate V. cholerae virulence.

bioRxiv · May 4, 2020Microbiology

Drug-like Fragments Inhibit agr-Mediated Virulence Expression in Staphylococcus aureus

I. F. Bezar, A. A. Mashruwala, J. M. Boyd, A. M. Stock

The paper tests five compound fragments for their ability to inhibit agr-mediated virulence in Staphylococcus aureus, finding three reduce agr-driven transcription and two lower secreted toxins.

bioRxiv · Feb 1, 2019Microbiology