Multi-domain touchscreen-based cognitive assessment of C57BL/6J female mice shows whole body exposure to 56Fe particle space radiation in maturity improves discrimination learning yet impairs stimulus-response habit learning
I. Soler, S. Yun, R. P. Raynolds, C. W. Whoolery, F. H. Tran, P. L. Kumar, Y. Rong, M. J. DeSalle, A. D. Gibson, A. M. Stowe, F. C. Kiffer, A. J. Eisch
This study shows that whole-body exposure to 56Fe radiation in mature female C57BL/6J mice improves hippocampal-dependent discrimination learning but impairs striatal-dependent rule-based learning.
bioRxiv · Jun 9, 2021Animal Behavior & Cognition